We will review and give some informations about Factors Contributing to The Development of Acne Vulgaris.

Acne vulgaris is a rather common skin disorder that is more widespread than many people may think. A large percentage of the global population suffers from AVP at one point in their lives; though some cases are more severe than others, and even some people who suffer from milder cases may still be afflicted with this skin condition.

Factors Contributing to The Development of Acne Vulgaris

Understanding the factors that contribute to the development of acne vulgaris will help individuals suffering from this skin disorder understand how to best deal with the problem.


For many years, doctors blamed adult women who suffered from acne for it being caused by hormones. However, modern medical science has shown that this is not the case. While it is true that adult females who suffer from acne experience higher levels of testosterone than normal, these levels are normal. The presence of hormones does not mean that they are causing the acne. In fact, there is a considerable amount of evidence that suggests that hormones play a small role in the cause of acne. But, the presence of hormones can contribute to the severity and frequency of the disease.

Acne Vulgaris Causes

Methylation of the Ratchet Rods of Membranes

This is one of the most well-known factors. When the skin produces a high amount of a particular protein called 5-alpha reductase (5 alpha Reductase), the skin’s sebaceous glands (the oil glands located in the hair follicles on the skin’s surface) become overactive. As a result, the skin produces more sebum (the skin’s natural moisturizing ingredient). The excess production of sebum, coupled with increased activity of the sebaceous glands, leads to clogged pores and the development of acne.

Cytoid Stem Cells

These cells appear in the blood stream and are responsible for many bodily actions. They release androgens that are involved in the formation of new skin cells. As a result, when they are overproduced, the person develops acne. Cytoid stem cells are found in both males and females.

Imprinted DNA

This refers to cells that contain within them an actual blueprint for growth. The acne causing germ (Propionibacterium acnes) has a specific genetic blueprint (genetic memory) that enables it to grow and spread quickly once it has taken up residence on the skin. This means that if you have acne, there is a good chance that some of your skin cells will be imprinted with the genetic blueprint for acne. Therefore, any treatments you need to use for acne vulgaris treatment will fail to work.


Corticotrophin is a group of chemicals and receptors that are present both in human and animals. They contribute to the formation of new skin cells. Also, they block the actions of other chemicals called prostaglandins. These two factors are what are known as pro-inflammatory and anti-inflammatory.

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