Medical Treatment For Tinnitus ;Acne disease combines different types of lesions that are composed, to varying degrees, of sebum retention, inflammation or infection of the pilosebaceous follicle.
Acne: a disease of the pilosebaceous follicle
Acne is a chronic disease that affects the pilosebaceous follicles, an assembly of the hair and the sebaceous gland in which each hair is associated with a gland that secretes sebum, an oily fluid whose normal function is to protect the body skin and which flows continuously where the hair emerges from the epidermis.
When the follicle is touched by acne, the hair canal (which allows the sebum to flow along the base of the hair to go to cover the skin) is clogged or congested by excessively viscous sebum or manufactured in excess and by dead skin cells. The disease essentially affects the face, but can also affect the forehead, back, back of the neck, front of the chest and forearms.
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Several types of lesions for the same disease: acne
Acne disease combines different types of lesions that are composed, to varying degrees, of sebum retention, inflammation or infection of the pilosebaceous follicle.
Retentional forms depend on the nature of the skin and hormones. The transition to inflammatory forms of the disease is due to the proliferation of a microbe, normally present in the skin’s glands: propionibacterium acnes.
Retentional acne: a simple accumulation of sebum
Seborrhea, literally the flow of sebum, is often the first manifestation of acne. The skin of the face is so bright and the pores dilated. This secretion of sebum takes place in the areas where the sebaceous glands are located: essentially the face, but also the anterior aspect of the thorax and the central part of the back. This modification of the texture of the skin concerns initially the central part of the face (the forehead, the tip of the nose, the cheeks and the chin). This excess of sebum is quickly accompanied by very small black dots called micro-comedones. The presence of fat or free fatty acids in the sebum is the ideal food for certain bacteria that will then be able to develop in the pilosebaceous follicles and prepare, at this stage, the inflammatory phase of acne.
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The black dot is called open comedo (or “skin worm”) because, when a black spot is pressed, a mixture of sebum and other cells that form the wall of the hair canal, the keratinocytes, comes out in the form a worm-like filament (this maneuver is not recommended, it may lead to a secondary infection). The black coloration is due to the oxidation of the keratinocytes contained in the sebum. The black dot is between 1 and 3 mm in diameter. At this stage, the conditions are met for the development of a bacterium, usually present in the follicle, propionibacterium acnes, and the comedone that is not treated is intended to evolve to the papule or pustule.
The micro-cyst or white point corresponds to a pilosebaceous follicle whose orifice of the hair canal is covered with cells of the epidermis (the upper part of the skin) which obturate it. The accumulation of sebum and keratin that continue to be secreted by the sebaceous gland induces an indurated and localized bulging of the skin centered by a pale zone, hence its name of white point. Here too, microbial growth (propionibacterium acnes) exists and makes the ground of the next phase that is inflammatory.