Treatment for Acne Vulgaris
Treatment for Acne Vulgaris should seek to improve physical appearance and reduce scarring and severity of inflamed skin lesions. The initial approach generally relies upon the degree of the acne, the patient’s treatment preferences, and age of the patient. Treatment may vary according to age and treatment success based upon these factors.
A majority of patients with mild acne vulgaris are treated with topical agents and in some cases oral antibiotics (tablets) are recommended. Treatment compliance varies according to the severity of acne vulgaris and varies according to adherence to treatment regimens. Treatment failure is rare in patients with allergic reactions to any of the antibiotics or topical treatment agents used. In addition, most patients experience improvement of their condition within a week of commencement of topical therapy and within several weeks after discontinuing such treatment. Generally, patients who respond to treatment do not require continued use beyond the initial four to six weeks of medication.
Mild to moderate acne vulgaris responds adequately to the use of oral antibiotics, with or without additional topical retinoid. Treatment is administered according to the management of each individual case by the dermatologist. Treatment for patients with severe acne vulgaris that fails to respond to initial antibiotic treatment may require isotretinoin or oral retinoids in combination with systemic antibiotics. Treatment for androgen excess is more difficult to achieve in this setting.
Localized treatment for severe acne vulgaris can include systemic enzyme levels control (serum provided daily or at alternate times), anti-inflammatory drugs and oral isotretinoin therapy. Oral isotretinoin therapy is usually started on days one and two of onset of severe acne, with maintenance dosage given through the course of therapy until the patient’s acne has improved to a level where it no longer requires the supplemental oral isotretinoin. Serotonin and adenosinephrine blockers are also sometimes used to prevent excessive sebum secretion. Patients with mild to moderate acne should not undergo prolonged therapy with these drugs.
The first study of isotretinoin was done in 2021 in the journal J Dermatol Venereol. A total of 6 subjects with vulgaris were randomly selected and treated with a single dose of isotretinoin. It was found that this dose of isotretinoin was effective in reducing facial pimples but not blackheads or nodules. Therefore, further studies are required to determine whether isotretinoin has a greater potential of reducing acne than the more widely used oral antibiotics.
There are currently no studies in the English literature comparing the effect of isotretinoin with that of topical antibiotics, such as erythromycin and clindamycin. However, all other studies with placebo controls have shown that acne vulgaris responds well to isotretinoin and all subjects had significantly better overall acne control than did patients who were treated with oral antibiotics. Therefore, the current consensus seems to be that isotretinoin may possibly be useful for the control of severe acne vulgaris in India. More research is needed to determine whether this treatment is more effective than other options.
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Treatment For Acne: Which Ones Work and Which Don’t
There are many reasons why acne treatment is necessary and even mandatory. The first and foremost reason is that no single acne cure works on everyone. Different people have different skin types, some may suffer from redness, others from inflammation, some may experience whiteheads while some may experience blackheads. The cause for these differences is mainly due to hormonal variations, clogged pores or follicles, sebum production and food habits.
There are several options available for the treatment of acne. There are four major scientifically proven pathological factors responsible for most acne that is why acne treatment nowadays is always the subject of scientific research. Since the public is showing an increased interest in safer and more natural acne treatment alternatives, the use of alternative and complementary medicines (CAMs) as a part of the acne treatment has also been a hot topic. However, the effectiveness of these CAMs still needs to be evaluated since they are new compounds that were not present before; therefore, the exact effects of these alternative therapies on your acne problem cannot yet be estimated.
The main goal of any form of treatment for acne is to reduce the production of sebum, control skin inflammations and reduce the presence of inflammatory enzymes. The effectiveness of a treatment mainly depends on how effectively it can achieve these goals. It is imperative that you consult your dermatologist if you want to use a medication that does not fit your specific skin type. A good example of such a type of medication is Retin-A. If you suffer from severe inflammatory skin lesions like acne scarring, Retin-A should not be used as it will only make things worse. On the other hand, if your acne condition is not so severe or if the lesions are mild, Retin-A can be good as Retin-A is able to bring about changes in the skin cells resulting in a temporary improvement of the condition; however, this form of treatment should only be done on a small scale until the desired results are achieved.