Which antibiotic is used to treat acne vulgaris? Which are the best choices for a cure for acne? This article will explore the causes of acne vulgaris, tell you how to avoid it and tell you what antibiotic is best to treat your acne. 


It was the first antibiotic used for acne vulgaris treatment. It works by killing the bacteria Propionibacterium acnes by using a complex mix of chemical compounds (which it calls azythromycin compounds). Erythromycin is not without its drawbacks though. It has produced gastrointestinal problems and has been linked to the formation of antibiotic-resistant strains of bacteria. Currently, clinical trials are underway to determine if there is any benefit to prescribing this drug for use in the treatment of acne without increasing the antibiotic resistance. 

Which Antibiotic Is Used to Treat Acne Vulgaris
Which Antibiotic Is Used to Treat Acne Vulgaris


It is one of the most commonly prescribed topical agents for acne. It works by destroying P. acnes by interfering with its ability to metabolize fatty acids. It has been shown to be effective in the treatment of vulgaris, though some researchers believe that it is overused due to the associated risks of side effects. Doxycycline was banned in some countries due to links to increased urinary tract infections. 

Oral contraceptives 

Some drugs, including oral contraceptives have been known to cause acne. Birth control pills, in particular, may cause serious menstrual disorders and irregularities that may lead to acne breakouts. So, while it may be tempting to treat acne using an oral contraceptive, speak to your doctor first. 

Prescription antibiotics 

Some antibiotics, including tetracycline, do have antibiotic effects. Your doctor will likely recommend a prescription antibiotic in case you have a severe case of vulgaris. However, many people prefer to take it as a preventive measure rather than a cure. Antibiotics like doxycycline, minocycline, ciprofloxacin and erythromycin may cause gastrointestinal upset, gas, and dizziness in some people. 

Combination medications 

It’s common for doctors to prescribe a combination of different oral medications in the battle against acne. Some examples include azathioprine/lorazepam and methotrexate/ isotretinoin. Azathioprine is an anti-inflammatory, while methotrexate is a kind of acid reducer. Your doctor will likely recommend that you combine the two in order to achieve maximum results. To find out more about which antibiotic is right for your case of vulgaris, use the Google Scholar Search feature to find an “antibiotic” and “combination” and then click on “study,” “cures” or “cured.” 

Topical antibiotics

In addition to topical antibiotics like benzoyl peroxide and erythromycin, there are oral antibiotics that can be used for acne treatment at home. Many people prefer to start with oral antibiotics because they don’t have the nasty side effects of topical antibiotics, such as burning, redness, blisters and stomach upset. However, topical antibiotics like benzoyl peroxide can also cause dryness and irritation in people who are allergic to them. If you’re unsure whether to start with an oral antibiotic or topical one, ask your doctor. 

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